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DR CALUX
The bioassay DR CALUX® (Dioxin Responsive Chemical Activated LUciferase gene eXpression) is used for quantification of dioxins/furans (PCDD/F) and dioxin-like PCBs (dl-PCBs). The difference between chemical analysis and the bioassay approach is illustrated in the figure below, based on EU-regulated 29 congeners of chlorinated compounds. DR CALUX measures the total toxic effect of a mixture (PXDD/F/dl-PXB) of dioxins, while chemical analysis (GC-MS) is focused on only certain compounds.
![DR_CALUX_01.jpg](https://static.wixstatic.com/media/8b2c54_8e555b86dbf04b0d8565e2b279fff560~mv2.jpg/v1/crop/x_253,y_0,w_1530,h_1238/fill/w_821,h_666,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/DR_CALUX_01.jpg)
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